Published In
Cerrahpaşa Medical Journal
Volume 29 · Issue 2
Pages: 75-78
History
Published Online: December 3, 2019
Copyright © 1998 Cerrahpaşa Medical Journal
Emel ZENGİN ULAKOĞLU
İÜ Cerrahpaşa Tıp Fakültesi Biyokimya Anabilim Dalı
Atilla SAYGI
Heybeliada Göğüs Hastalıkları ve Göğüs Cerrahisi Merkezi
M. Koray GÜMÜŞTAŞ
İÜ Cerrahpaşa Tıp Fakültesi Biyokimya Anabilim Dalı
Erkan ZOR
Heybeliada Göğüs Hastalıkları ve Göğüs Cerrahisi Merkezi
Asuman AKKAYA
İÜ Cerrahpaşa Tıp Fakültesi Biyokimya Anabilim Dalı
Emine KÖKOĞLU
İÜ Cerrahpaşa Tıp Fakültesi Biyokimya Anabilim Dalı
ZENGİN ULAKOĞLU, E., SAYGI, A., GÜMÜŞTAŞ, M. K., ZOR, E., AKKAYA, A., & KÖKOĞLU, E. (2019). KRONİK TİNER İNHALASYONUNUN SIÇAN AKCİĞER VE KARACİĞER DOKULARI LİPİD PEROKSİDASYONLARINA ETKİSİ. Cerrahpaşa Medical Journal, 29(2), 75–78. Retrieved from https://cerrahpasamedj.org/index.php/pub/article/view/12
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Abstract
Background and Design. We studied the effect of chronic thinner inhalation (during 5 weeks) on lipid peroxidation in the lung and liver of the rats. Additionally, we studied superoxide dismutase (SOD) activities and reduced glutathione (CSH) levels.
Results. Significant increases were found in lipid peroxidation (TBA RS) levels of rats which had inhaled thinner compared to those of the control group (p=0.000). As opposed to increases in the TBARS levels, significant decreases in the SOD activities and GSH levels were observed when compared to the rats in the control group (p=0.000).
Conclusion. Increases in peroxidative damage due to the reactive oxygen species generation and decreases in the antioxidant capacity may be the cause of some progressive dysfunction in these tissues.
Article Info
Published In
Journal
Cerrahpaşa Medical Journal
Volume / Issue
Volume 29 · Issue 2
Pages
75-78
History
Published Online
December 3, 2019
Copyright
Copyright (c) 1998 Cerrahpaşa Medical Journal
Affiliations
Emel ZENGİN ULAKOĞLU
İÜ Cerrahpaşa Tıp Fakültesi Biyokimya Anabilim Dalı
Atilla SAYGI
Heybeliada Göğüs Hastalıkları ve Göğüs Cerrahisi Merkezi
M. Koray GÜMÜŞTAŞ
İÜ Cerrahpaşa Tıp Fakültesi Biyokimya Anabilim Dalı
Erkan ZOR
Heybeliada Göğüs Hastalıkları ve Göğüs Cerrahisi Merkezi
Asuman AKKAYA
İÜ Cerrahpaşa Tıp Fakültesi Biyokimya Anabilim Dalı
Emine KÖKOĞLU
İÜ Cerrahpaşa Tıp Fakültesi Biyokimya Anabilim Dalı
Cite this Article
ZENGİN ULAKOĞLU, E., SAYGI, A., GÜMÜŞTAŞ, M. K., ZOR, E., AKKAYA, A., & KÖKOĞLU, E. (2019). KRONİK TİNER İNHALASYONUNUN SIÇAN AKCİĞER VE KARACİĞER DOKULARI LİPİD PEROKSİDASYONLARINA ETKİSİ. Cerrahpaşa Medical Journal, 29(2), 75–78. Retrieved from https://cerrahpasamedj.org/index.php/pub/article/view/12
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