Background and Design. The presence of Cryptococcus neoformans in its natural habitats in Istanbul was studied in modified StaibSeeliger medium (Guizotia abyssinicadiphenylcreatininantibioticdextroseagar). A total of 100 samples (49 from open area, 42 from coops, 2 from nests and 7 from soil) were cultured and C. neoformans was isolated.
Results. Cryptococcus neoformans was isolated only in a single sample obtained from coop (1 %). The frequency of this fungus in coops was determined as 2.3% (1/42).