Cerrahpaşa Medical Journal
CASE REPORT

ASPERGILLUS CINSI MANTARLAR VE İNVAZİV ASPERGİLLOZ: MİKOLOJİ, PATOGENEZ, LABORATUVAR TANIMI, ANTİFUNGALLERE DİRENÇ VE DUYARLILIK DENEYLERİ

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İ.Ü. Cerrahpaşa Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, İstanbul

Cerrahpasa Med J 2003; 34: 140-157
Read: 1335 Downloads: 596 Published: 27 July 2014

Background and Design.- Aspergillus species has become one of the most important airborne pathogen in developed countries, causing a significant increase in fatal pulmonary invazive aspergillosis. In spite of the recent progress in the study of laboratory diagnosis and antifungal treatments invazive aspergillosis tends to occur in immunologically debilitated individuals with an overall mortality of >50% and a mortality approaching 100% in allogenic bone marrow transplant patients. This paper briefly reviews the current state of knowledge regarding Aspergillus species and invazive aspergillosis focusing on the mycology, pathogenesis, laboratory diagnosis, antifungal agents and susceptibility tests.

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EISSN 2687-1904